mood disorders

Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html

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Study Counts

Type	Study_count
Total_Studies	309
interventional	230
Observational	71
Registry	8

Studies over Time by Start Date

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Interventional Trials

Intervention Type

intervention_type	Study_Count
Behavioral	75
Drug	41
Drug|placebo	39
Device	26
Other	19
Behavioral|Other	7
Dietary Supplement|placebo	6
Behavioral|Drug	3
Procedure	3
Behavioral|Device	2
Behavioral|Device|Drug|Radiation	1
Behavioral|Device|Other	1
Behavioral|Drug|placebo	1
Biological	1
Combination Product	1
Device|Other	1
Device|placebo	1
Drug|Other|placebo	1
Other|placebo	1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country	Study_Count
United States	115
NA	13
Canada	12
Denmark	9
Switzerland	9
United Kingdom	7
Australia	5
France	5
Spain	5
Netherlands	4
Austria	3
Germany	3
Norway	3
Belgium	2
Finland	2
Hong Kong	2
India	2
Pakistan	2
Poland	2
United States|Canada	2
United States|Canada|Netherlands	2
Australia|Austria|Norway	1
Brazil	1
China	1
Croatia	1
Germany|Poland|Russian Federation|United States|Canada|France|Serbia	1
Germany|Switzerland	1
Ghana	1
Israel|Romania	1
Kosovo	1
Portugal	1
Romania	1
South Africa	1
Sweden	1
Taiwan	1
Tanzania	1
United States|Canada|France|Germany|Hungary|Poland|Romania|Russian Federation|Serbia|Slovakia|Ukraine	1
United States|Canada|France|Poland|Slovakia	1
United States|Canada|Germany|Hungary|Romania|Russian Federation|Ukraine	1
United States|Egypt|India	1
United States|Germany|Hungary|Poland|Slovakia	1
United States|Greece|Korea, Republic of|Lithuania|Russian Federation|Taiwan|Turkey|Ukraine	1

Sites per Study

Site_count	Study_Count
1	176
2	22
3	7
4	6
5	4
8	1
10	1
14	1
15	1
16	1
18	1
33	1
47	2
51	1
54	1
57	1
71	1
76	1
144	1

Phase

Phase	Study_Count
N/A	127
Phase 2	28
Phase 4	22
Phase 3	17
Phase 1	16
Phase 2/Phase 3	9
Phase 1/Phase 2	7
Early Phase 1	4

Number of Arms

Number_of_Arms	Count_of_Studies
1	43
2	130
3	25
4	8
5	1
6	1
NA	22

Enrollment Metrics by Phase

Measure	Early.Phase.1	N.A	Phase.1	Phase.1.Phase.2	Phase.2	Phase.2.Phase.3	Phase.3	Phase.4
Min.	14.0	7.0000	16.0000	5	2.00000	40.0000	13.000	20.0000
1st Qu.	18.5	40.0000	16.0000	50	27.75000	94.0000	91.500	40.2500
Median	22.0	60.0000	28.0000	67	68.00000	100.0000	369.000	55.0000
Mean	22.0	115.0551	38.6875	102	77.39286	125.1111	676.375	128.7273
3rd Qu.	25.5	136.0000	42.0000	136	91.00000	160.0000	828.750	101.7500
Max.	30.0	952.0000	165.0000	270	307.00000	275.0000	2944.000	1126.0000

Trial Group Type

group_type	Group_Count
Experimental	199
Active Comparator	99
Placebo Comparator	56
No Intervention	39
NA	22
Other	20
Sham Comparator	8

Intervention Model

intervention_model	Study_Count
Parallel Assignment	154
Single Group Assignment	42
Crossover Assignment	25
NA	5
Factorial Assignment	4

Primary Purpose

primary_purpose	Study_Count
Treatment	151
Basic Science	20
Health Services Research	20
Other	13
Prevention	12
Supportive Care	6
Diagnostic	3
NA	3
Device Feasibility	1
Screening	1

Observational Studies

Studies by Country

Country	Study_Count
United States	42
NA	5
Canada	4
France	3
China	2
Israel	2
Australia	1
Austria	1
Brazil	1
Chile	1
Croatia	1
Denmark	1
Germany	1
Japan	1
Norway	1
Switzerland	1
United Kingdom	1
United States|Canada|Norway	1
United States|France|Russian Federation	1

Sites per Study

Site_count	Study_Count
1	63
2	4
3	2
7	1
10	1

Enrollment Metrics

Measure	Observational
Min	4.000
1st Qu	46.000
Median	115.000
Mean	800.169
3rd Qu	400.000
Max	16000.000

Observation Model

observational_model	Study_Count
Cohort	34
NA	16
Case-Control	6
Case-Only	6
Case Control	3
Other	2
Case-Crossover	1
Defined Population	1
Ecologic or Community	1
Family-Based	1

Time Perspective

time_perspective	Study_Count
Prospective	38
NA	15
Cross-Sectional	6
Retrospective	6
Other	5
Cross-Sectional, Prospective	1

Registries

Studies by Country

Country	Study_Count
United States	3
Canada	1
China	1
Korea, Republic of	1
NA	1
Poland	1

Sites per Study

Site_count	Study_Count
1	8

Enrollment Metrics

Measure	Registries
Min	80.0
1st Qu	115.0
Median	1000.0
Mean	747289.4
3rd Qu	11787.0
Max	5940299.0

Registry Model

observational_model	Study_Count
Cohort	5
Other	2
Case-Only	1

Time Perspective

time_perspective	Study_Count
Prospective	5
Cross-Sectional	2
Other	1

Follow-up

target_duration	Study_Count
1 Year	2
10 Years	2
1 Week	1
17 Years	1
3 Years	1
7 Days	1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id	brief_title	link	overall_status	source	primary_completion_date
NCT03591224	Pharmacogenomic Testing to Optimize Antidepressant Drug Therapy	https://ClinicalTrials.gov/show/NCT03591224	Completed	John Papastergiou Pharmacy Ltd	2019-12-31
NCT03346291	Examining Persistence in Smokers With Schizophrenia	https://ClinicalTrials.gov/show/NCT03346291	Completed	Rutgers, The State University of New Jersey	2018-06-13
NCT03943537	Effects of Intranasal Insulin on Neuroimaging Markers and Cognition in Patients With Psychotic Disorders	https://ClinicalTrials.gov/show/NCT03943537	Recruiting	Mclean Hospital	2020-12-31
NCT03820297	Anti-stigma Intervention for Chinese American Older Adults	https://ClinicalTrials.gov/show/NCT03820297	Completed	NYU Langone Health	2020-03-13
NCT03338673	Brain Stimulation and Cognitive Training	https://ClinicalTrials.gov/show/NCT03338673	Completed	University of Michigan	2019-09-27
NCT03313674	Investigation of Seasonal Variations of Brain Structure and Connectivity in SAD	https://ClinicalTrials.gov/show/NCT03313674	Enrolling by invitation	Sunnybrook Health Sciences Centre	2019-10-05
NCT03300440	PROVIT The Influence of Probiotics on Body and Mind in Individuals With Psychiatric Disorders	https://ClinicalTrials.gov/show/NCT03300440	Active, not recruiting	Medical University of Graz	2018-08-01
NCT03285516	Safety Aid Reduction Treatment for Rural Veterans	https://ClinicalTrials.gov/show/NCT03285516	Completed	Southeast Louisiana Veterans Health Care System	2019-04-02
NCT03275714	Evaluation of an App for Smartphones for People With a Bipolar Affective Disorder	https://ClinicalTrials.gov/show/NCT03275714	Completed	Medical University of Graz	2019-11-20
NCT03261817	A Controlled Study With Remote Web-based Adapted Physical Activity (e-APA) in Psychotic Disorders	https://ClinicalTrials.gov/show/NCT03261817	Recruiting	University Hospital, Caen	2021-12-31
NCT03260985	Precision Psychiatry Continuity Clinic Project	https://ClinicalTrials.gov/show/NCT03260985	Completed	Stanford University	2019-12-01
NCT03249857	Study of Sensorimotor Compatibility Effects in Bipolar Affective Disorder.	https://ClinicalTrials.gov/show/NCT03249857	Completed	Centre Hospitalier Universitaire de Saint Etienne	2018-08-21
NCT03228394	A Clinical Trial of Intravenous Ganaxolone in Women With Postpartum Depression	https://ClinicalTrials.gov/show/NCT03228394	Completed	Marinus Pharmaceuticals	2019-06-20
NCT03221270	Targeting Auditory Hallucinations With Alternating Current Stimulation	https://ClinicalTrials.gov/show/NCT03221270	Recruiting	University of North Carolina, Chapel Hill	2021-10-31
NCT03198936	To Access the Effect of Brain Pillâ„¢ on Working Memory Capacity and Mood Behaviour.	https://ClinicalTrials.gov/show/NCT03198936	Completed	Vedic Lifesciences Pvt. Ltd.	2017-11-17
NCT03183609	Confirmatory Efficacy Trial of a Gluten-Free Diet in a Subgroup of Persons With Schizophrenia Who Have High Levels of IgG Anti-Gliadin Antibodies (AGA IG)	https://ClinicalTrials.gov/show/NCT03183609	Recruiting	University of Maryland, Baltimore	2022-07-30
NCT03183388	Brain Emotion Circuitry-Targeted Self-Monitoring and Regulation Therapy (BE-SMART)	https://ClinicalTrials.gov/show/NCT03183388	Recruiting	Yale University	2021-06-30
NCT03163940	Laughter Yoga Intervention for People With Major Depressive Disorder	https://ClinicalTrials.gov/show/NCT03163940	Completed	The Hong Kong Polytechnic University	2018-08-01
NCT03129360	Levetiracetam in Early Psychosis	https://ClinicalTrials.gov/show/NCT03129360	Recruiting	NYU Langone Health	2019-10-30
NCT01816087	Performances of a Brief Assessment Tool for the Early Diagnosis of Geriatric Syndromes by Primary Care Physicians	https://ClinicalTrials.gov/show/NCT01816087	Completed	University of Lausanne	2014-11-30
NCT03109028	Mental Health in Refugees and Asylum Seekers	https://ClinicalTrials.gov/show/NCT03109028	Recruiting	Charite University, Berlin, Germany	2019-10-31
NCT03102008	Unified Protocol for Adolescents (UP-A) Change Processes	https://ClinicalTrials.gov/show/NCT03102008	Completed	University of Miami	2017-12-14
NCT03064477	The Unified Protocol for the Treatment of Emotional Disorders in Spanish Public Mental Health System	https://ClinicalTrials.gov/show/NCT03064477	Recruiting	Universitat Jaume I	2021-09-30
NCT03059771	Mobile Enhancement of Motivation in Schizophrenia	https://ClinicalTrials.gov/show/NCT03059771	Completed	Indiana University	2018-01-16
NCT03033420	Reducing the Rate and Duration of Re-ADMISsions Among Patients With Unipolar Disorder and Bipolar Disorder Using Smartphone-based Monitoring and Treatment - The RADMIS Trials	https://ClinicalTrials.gov/show/NCT03033420	Active, not recruiting	Psychiatric Centre Rigshospitalet	2020-03-01
NCT03000894	CBT-I as Early Intervention of Mood Disorders	https://ClinicalTrials.gov/show/NCT03000894	Completed	The University of Hong Kong	2020-01-31
NCT02948036	A Closed-loop Assessment and Treatment Platform for Mood Disorders	https://ClinicalTrials.gov/show/NCT02948036	Active, not recruiting	Posit Science Corporation	2020-03-30
NCT02928159	Low Pulse Amplitude Seizure Therapy (LAP-ST Study)	https://ClinicalTrials.gov/show/NCT02928159	Completed	Behman Hospital	2015-06-30
NCT02917499	Efficacy and Safety of TMS and Deep TMS Treatment for Psychiatric and Neurological Disorders	https://ClinicalTrials.gov/show/NCT02917499	Completed	Sveti Ivan Psychiatric Hospital	2018-01-31
NCT02870283	Cost- Effectiveness and Quality of Life Assessment in Mood Disorder	https://ClinicalTrials.gov/show/NCT02870283	Completed	Federal University of Rio Grande do Sul	2014-11-30
NCT02824627	Oxytocin on Irritability/Emotional Dysregulation of Disruptive Behavior and Mood Disorders	https://ClinicalTrials.gov/show/NCT02824627	Recruiting	University of Nebraska	2020-01-31
NCT02819986	Effectiveness of Using the Progressive Goal Attainment Program in Anxiety and Mood Disorders	https://ClinicalTrials.gov/show/NCT02819986	Completed	St. Joseph’s Healthcare Hamilton	2019-04-30
NCT02817438	Research on Anxiety and Depression: Computer-Assisted Therapy	https://ClinicalTrials.gov/show/NCT02817438	Completed	Stanford University	2018-03-31
NCT02782442	Cognitive Training Delivered Remotely to Individuals With Psychosis (ROAM)	https://ClinicalTrials.gov/show/NCT02782442	Recruiting	University of Minnesota	2020-09-30
NCT02766101	Manville Moves: an Exercise Intervention for Behavioral Regulation Among Children With Behavioral Health Challenges	https://ClinicalTrials.gov/show/NCT02766101	Completed	Harvard School of Public Health	2015-04-30
NCT02752295	Intensive Stress Coping Intervention Week - A Secondary Prevention For Real World Affective Disorder Patients	https://ClinicalTrials.gov/show/NCT02752295	Completed	Medical University of Vienna	2016-07-31
NCT02734602	Imaging SV2A in Mood Disorders	https://ClinicalTrials.gov/show/NCT02734602	Recruiting	Yale University	2021-01-31
NCT02703363	Minocycline and Celecoxib as Adjunctive Treatments of Bipolar Depression	https://ClinicalTrials.gov/show/NCT02703363	Completed	Pakistan Institute of Living and Learning	2018-12-31
NCT02675257	Depression and Diabetes Control Trial	https://ClinicalTrials.gov/show/NCT02675257	Completed	Forschungsinstitut der Diabetes Akademie Mergentheim	2018-03-31
NCT02664467	Chronobiology, Sleep Related Risk Factors and Light Therapy in Perinatal Depression: the Life-ON Project	https://ClinicalTrials.gov/show/NCT02664467	Active, not recruiting	Ospedale Regionale di Lugano	2018-11-30
NCT02658357	Study in Stabilized Schizophrenic Patients to Evaluate the Pharmacokinetics of Risperidone and 9-Hydroxy (OH)-Risperidone When Risperidone is Administered From a Polyurethane Implant	https://ClinicalTrials.gov/show/NCT02658357	Completed	Braeburn Pharmaceuticals	2017-08-31
NCT02631291	Promoting Widowed Elders Lifestyle After Loss	https://ClinicalTrials.gov/show/NCT02631291	Completed	University of Pittsburgh	2019-05-17
NCT02610725	Online Yoga for Individuals With Mood Disorders	https://ClinicalTrials.gov/show/NCT02610725	Completed	Massachusetts General Hospital	2018-02-20
NCT02593734	Integrating Psychotropic Medication Into the Care of People With Mental Disorders in a Prayer Camp in Ghana	https://ClinicalTrials.gov/show/NCT02593734	Completed	University of Ghana Medical School	2015-07-31
NCT02582398	Influence of Light Exposure on Cerebral MAO-A in Seasonal Affective Disorder and Healthy Controls Measured by PET	https://ClinicalTrials.gov/show/NCT02582398	Completed	Medical University of Vienna	2017-04-03
NCT03403959	Seasonal Affective Disorder and Visual Impairment	https://ClinicalTrials.gov/show/NCT03403959	Recruiting	Psychiatric Centre Rigshospitalet	2020-03-01
NCT00747396	The Bucharest Early Intervention Project	https://ClinicalTrials.gov/show/NCT00747396	Active, not recruiting	Boston Children’s Hospital	2025-03-31
NCT02542475	Low Field Magnetic Stimulation: Open Label Study.	https://ClinicalTrials.gov/show/NCT02542475	Active, not recruiting	Mclean Hospital	2019-08-31
NCT02537093	Pilot Study of Asynchronous and Synchronous Telepsychiatry for Skilled Nursing Facilities	https://ClinicalTrials.gov/show/NCT02537093	Completed	University of California, Davis	2017-05-31
NCT02474524	Self-Management and Recovery Technology Psychosocial Intervention Trial	https://ClinicalTrials.gov/show/NCT02474524	Completed	Swinburne University of Technology	2017-06-30
NCT02453217	The Potential Efficacy of the Chinese Health Improvement Profile- A Pilot Clustered Randomised Controlled Trial	https://ClinicalTrials.gov/show/NCT02453217	Completed	The Hong Kong Polytechnic University	2018-11-30
NCT02349880	A Shared Decision-making Training for Inpatients With Schizophrenia	https://ClinicalTrials.gov/show/NCT02349880	Completed	Technische Universität München	2014-12-31
NCT02263872	Minocycline as an Adjunct for the Treatment of Depressive Symptoms: Pilot Randomized Controlled Trial	https://ClinicalTrials.gov/show/NCT02263872	Completed	Pakistan Institute of Living and Learning	2016-06-30
NCT02232737	Project 3, Study 2: Extended Exposure to Low Nicotine Content Cigarettes in People With Current Affective Disorders	https://ClinicalTrials.gov/show/NCT02232737	Completed	Brown University	2019-01-14
NCT02196506	Study of the Safety and Efficacy of Fixed-dose Brexpiprazole (OPC-34712) as Adjunctive Therapy in the Treatment of Adults With Major Depressive Disorder With and Without Anxious Distress	https://ClinicalTrials.gov/show/NCT02196506	Completed	Otsuka Pharmaceutical Development & Commercialization, Inc.	2016-04-30
NCT02189057	A Pharmacokinetic/Pharmacodynamic Genetic Variation Treatment Algorithm Versus Treatment As Usual for Management Of Depression	https://ClinicalTrials.gov/show/NCT02189057	Completed	Mayo Clinic	2018-10-19
NCT02150681	Mindfulness-Based Cognitive Therapy for Perinatal Women With Mood Disorders	https://ClinicalTrials.gov/show/NCT02150681	Completed	University of California, Los Angeles	2013-10-31
NCT02097563	Family-Focused Therapy for Youth With Early-Onset Bipolar or Psychotic Disorders	https://ClinicalTrials.gov/show/NCT02097563	Completed	University of California, Los Angeles	2019-01-31
NCT02084979	A Controlled Trial of Patient Centered Telepsychiatry Interventions	https://ClinicalTrials.gov/show/NCT02084979	Completed	University of California, Davis	2017-12-31
NCT02077829	Implementation of Illness Management and Recovery in Mental Health Services	https://ClinicalTrials.gov/show/NCT02077829	Completed	University Hospital, Akershus	2015-06-30
NCT02069912	Multifaceted Depression and Cardiovascular Program	https://ClinicalTrials.gov/show/NCT02069912	Completed	University of Southern California	2009-02-28
NCT01315028	Bipolar Intervention Study: Cognitive Interpersonal Therapy	https://ClinicalTrials.gov/show/NCT01315028	Completed	NHS Greater Glasgow and Clyde	2011-10-31
NCT01293409	Bright Light Therapy in Seasonal Affective Disorder (SAD)	https://ClinicalTrials.gov/show/NCT01293409	Completed	University of Oulu	2011-03-31
NCT01270672	Pharmacological Interaction Between Carvedilol and Methylenedioxymethamphetamine (MDMA)	https://ClinicalTrials.gov/show/NCT01270672	Completed	University Hospital, Basel, Switzerland	2011-05-31
NCT01995916	Wellness Intervention for Menstrual Mood Disorders	https://ClinicalTrials.gov/show/NCT01995916	Completed	University of North Carolina, Chapel Hill	2018-05-31
NCT01951508	Effects of Methylphenidate, Modafinil, and MDMA on Emotion-processing in Humans: A Pharmaco-fMRI Study	https://ClinicalTrials.gov/show/NCT01951508	Completed	University Hospital, Basel, Switzerland	2014-12-31
NCT01903096	Treating Emotional Disorders in Primary Care With Psychological Techniques	https://ClinicalTrials.gov/show/NCT01903096	Completed	Psicofundación: Fundación Española para Promoción, Desarrollo Científico y Profesional de la Psicolo	2018-07-30
NCT01882608	Using Mental Health Telemetry to Predict Relapse and Re-hospitalization in Mood Disorders	https://ClinicalTrials.gov/show/NCT01882608	Completed	Sunnybrook Health Sciences Centre	2016-03-31
NCT01879800	One-Day Acceptance and Commitment Training Intervention in Primary Care Patients	https://ClinicalTrials.gov/show/NCT01879800	Completed	University of Iowa	2013-12-31
NCT01820286	Positive Psychology for Mood Disorders	https://ClinicalTrials.gov/show/NCT01820286	Completed	Massachusetts General Hospital	2016-06-10
NCT01815398	Cognitive Skills Training for Homeless Youth	https://ClinicalTrials.gov/show/NCT01815398	Completed	New York State Psychiatric Institute	2015-12-31
NCT01784705	Transcranial Bright Light Therapy in Seasonal Affective Disorder (SAD)	https://ClinicalTrials.gov/show/NCT01784705	Completed	University of Oulu	2013-03-31
NCT01746303	Omega-3 and Blueberry Supplementation in Age-Related Cognitive Decline	https://ClinicalTrials.gov/show/NCT01746303	Completed	University of Cincinnati	2016-01-31
NCT01731119	Study of Lurasidone in Treating Antipsychotic Naive or Quasi-Naive Children and Adolescents	https://ClinicalTrials.gov/show/NCT01731119	Completed	University of North Carolina, Chapel Hill	2014-08-31
NCT01727726	A Study of Flexible-dose Brexpiprazole as Adjunctive Therapy in the Treatment of Adults With Major Depressive Disorder, the Delphinus Trial	https://ClinicalTrials.gov/show/NCT01727726	Completed	Otsuka Pharmaceutical Development & Commercialization, Inc.	2016-10-17
NCT01722344	Improving Work Outcome for People With Severe Mental Illness	https://ClinicalTrials.gov/show/NCT01722344	Active, not recruiting	Mental Health Centre Copenhagen	2017-08-31
NCT01721824	The Effect of IPS-MA- A Modified Early Supported Employment Intervention for Individuals With Mood or Anxiety Disorders	https://ClinicalTrials.gov/show/NCT01721824	Completed	Mental Health Centre Copenhagen	2016-03-31
NCT01720316	Neurobiology of a Mutation in Glycine Metabolism in Psychotic Disorders	https://ClinicalTrials.gov/show/NCT01720316	Completed	Mclean Hospital	2017-05-31
NCT01696578	Effectiveness of Combined Intervention Approaches in the Treatment of Affective Disorders and Chronic Pain in War Victims	https://ClinicalTrials.gov/show/NCT01696578	Completed	Rehabilitation and Research Centre for Torture Victims	2012-12-31
NCT01615458	Disseminating Evidence-based Mood Disorder Chronic Care Models	https://ClinicalTrials.gov/show/NCT01615458	Completed	University of Michigan	2012-05-31
NCT01559857	Pioglitazone in Patients With Mood Disorders	https://ClinicalTrials.gov/show/NCT01559857	Completed	Stanford University	2014-01-31
NCT01473550	Mental Health Engagement Network (MHEN)	https://ClinicalTrials.gov/show/NCT01473550	Completed	Lawson Health Research Institute	2014-06-30
NCT01462305	30-Minute Light Exposure for the Treatment of Seasonal Affective Disorder	https://ClinicalTrials.gov/show/NCT01462305	Completed	Philips Respironics	2012-04-02
NCT01462058	The Role of Vitamin D Supplementation on Well Being and Symptoms of Depression During the Winter Season in Health Service Staff	https://ClinicalTrials.gov/show/NCT01462058	Completed	Region Syddanmark	2012-03-31
NCT01431092	Melatonin Versus Placebo for Benzodiazepine Discontinuation in Patients With Schizophrenia	https://ClinicalTrials.gov/show/NCT01431092	Completed	University of Copenhagen	2014-06-30
NCT01386177	Pharmacological Interaction Between Doxazosin and Methylenedioxymethamphetamine (MDMA)	https://ClinicalTrials.gov/show/NCT01386177	Completed	University Hospital, Basel, Switzerland	2012-01-31
NCT01360866	Safety and Tolerability of Oral OPC-34712 as Adjunctive Therapy in Adults With Major Depressive Disorder (the Orion Trial)	https://ClinicalTrials.gov/show/NCT01360866	Completed	Otsuka Pharmaceutical Development & Commercialization, Inc.	2017-04-18
NCT01360645	Study of the Safety and Efficacy of Fixed Dose OPC-34712 as Adjunctive Therapy in the Treatment of Adults With Major Depressive Disorder (the Pyxis Trial)	https://ClinicalTrials.gov/show/NCT01360645	Completed	Otsuka Pharmaceutical Development & Commercialization, Inc.	2013-05-31
NCT01360632	Study of the Safety and Efficacy of Two Fixed Doses of OPC-34712 as Adjunctive Therapy in the Treatment of Adults With Major Depressive Disorder (the Polaris Trial)	https://ClinicalTrials.gov/show/NCT01360632	Completed	Otsuka Pharmaceutical Development & Commercialization, Inc.	2013-08-31
NCT01324973	Web-Based Weight Management for Individuals With Mental Illness	https://ClinicalTrials.gov/show/NCT01324973	Completed	University of California, Los Angeles	2014-04-30
NCT04343391	Brief Psychotherapies for Emotional Disorders in Primary and Secondary Care	https://ClinicalTrials.gov/show/NCT04343391	Recruiting	Universidad de Córdoba	2020-05-15
NCT04327843	Reducing the Burden of Chronic Psychotic Disorders in Tanzania (CAPACITY)	https://ClinicalTrials.gov/show/NCT04327843	Active, not recruiting	Case Western Reserve University	2020-09-30
NCT04325100	Intervention Targeting Motivational Negative Symptoms	https://ClinicalTrials.gov/show/NCT04325100	Completed	University of Liege	2019-12-06
NCT04313777	Virtual Reality Therapy in Cardiology	https://ClinicalTrials.gov/show/NCT04313777	Completed	University School of Physical Education in Wroclaw	2020-03-13
NCT04251000	Infrared Photomodulation Therapy for Seasonal Affective Disorder	https://ClinicalTrials.gov/show/NCT04251000	Recruiting	ProofPilot	2020-05-31
NCT04242550	Binge Eating Anxiety and Mood	https://ClinicalTrials.gov/show/NCT04242550	Recruiting	University of California, San Diego	2022-01-01
NCT04222816	Effect of Regulated Add -on Sodium Chloride Intake on Stabilization of Serum Lithium Concentration in Bipolar Disorder	https://ClinicalTrials.gov/show/NCT04222816	Recruiting	All India Institute of Medical Sciences, Bhubaneswar	2021-12-15
NCT04210557	Models of Auditory Hallucination	https://ClinicalTrials.gov/show/NCT04210557	Recruiting	Yale University	2021-06-30
NCT04191876	Financial Incentives to Improve Medication Adherence	https://ClinicalTrials.gov/show/NCT04191876	Recruiting	Northwell Health	2020-03-30
NCT04136054	Better Sleep in Psychiatric Care - Anxiety and Affective Disorders	https://ClinicalTrials.gov/show/NCT04136054	Enrolling by invitation	Karolinska Institutet	2022-12-31
NCT04113993	Bazedoxifene -Treatment for Women With Schizophrenia	https://ClinicalTrials.gov/show/NCT04113993	Recruiting	The Alfred	2022-12-31
NCT04113967	Efficacy of a Biodanza Program in People With Alzheimer’s Disease.	https://ClinicalTrials.gov/show/NCT04113967	Completed	Universidad de Almeria	2018-07-01
NCT04076839	The Effectiveness of a Cognitive Training Program, Goal Management Training, on Reducing Cognitive Difficulties and Improving Every-day Functioning in Individuals With Affective Disorders	https://ClinicalTrials.gov/show/NCT04076839	Completed	Homewood Research Institute	2019-07-23
NCT04066985	Targeting Adolescent Depressive Symptoms Via Brief, Web-Based Interventions	https://ClinicalTrials.gov/show/NCT04066985	Recruiting	Child Mind Institute	2020-10-31
NCT04054973	L-arginine Study for Persistent Symptoms of Schizophrenia	https://ClinicalTrials.gov/show/NCT04054973	Recruiting	University of Massachusetts, Worcester	2020-07-31
NCT04045977	Virtual Therapy as a Method Supporting the Cardiac Rehabilitation	https://ClinicalTrials.gov/show/NCT04045977	Completed	University School of Physical Education in Wroclaw	2019-09-30
NCT04006756	A Study on Better Cognitive Functioning Through Braintraining on the Internet	https://ClinicalTrials.gov/show/NCT04006756	Recruiting	VU University Medical Center	2020-09-30
NCT04004416	Multi-modal Assessment of Gamma-aminobutyric Acid (GABA) Function in Psychosis	https://ClinicalTrials.gov/show/NCT04004416	Recruiting	University of Michigan	2025-03-31
NCT03995186	Effects of Behavioural Activation on Emotional Cognition and Mood	https://ClinicalTrials.gov/show/NCT03995186	Recruiting	University of Oxford	2021-03-30
NCT03969589	Reproductive Life Planning for Women With Mental Illness	https://ClinicalTrials.gov/show/NCT03969589	Active, not recruiting	VA Office of Research and Development	2020-07-31
NCT03964246	Compassion Meditation for Older Adults	https://ClinicalTrials.gov/show/NCT03964246	Enrolling by invitation	VA Office of Research and Development	2021-05-30
NCT03913013	Technology Enhanced Family Treatment	https://ClinicalTrials.gov/show/NCT03913013	Recruiting	University of California, Los Angeles	2021-11-14
NCT03911414	A Clinical Trial Via Telepsychiatry of Treatments for the Management of Emotional Dysregulation in Youth	https://ClinicalTrials.gov/show/NCT03911414	Recruiting	Massachusetts General Hospital	2021-05-31
NCT03881449	DIMES - DIgital MEdicine Study for Adults With Schizophrenia, Bipolar I Disorder, or Major Depression Currently Using Aripiprazole	https://ClinicalTrials.gov/show/NCT03881449	Active, not recruiting	Durham VA Medical Center	2021-01-31
NCT03868839	Telmisartan Pilot Study on Treatment Resistant Schizophrenia	https://ClinicalTrials.gov/show/NCT03868839	Active, not recruiting	University of Massachusetts, Worcester	2020-02-01
NCT03863366	Effects of Acute Prucalopride Administration in Healthy Volunteers	https://ClinicalTrials.gov/show/NCT03863366	Completed	University of Oxford	2017-08-08
NCT03860597	Memantine Effects on Sensorimotor Gating and Neurocognition in Schizophrenia	https://ClinicalTrials.gov/show/NCT03860597	Recruiting	University of California, San Diego	2021-03-31
NCT03859297	Mechanisms of Rumination Change in Adolescent Depression	https://ClinicalTrials.gov/show/NCT03859297	Recruiting	University of Utah	2024-03-31
NCT03803189	Proactive, Personalized Postpartum Mental Healthcare	https://ClinicalTrials.gov/show/NCT03803189	Recruiting	Women’s College Hospital	2021-01-31
NCT03800303	Integrated Treatment for Youth With Mood Disorders	https://ClinicalTrials.gov/show/NCT03800303	Active, not recruiting	Mayo Clinic	2020-09-30
NCT03794076	Cromoglycate Adjunctive Therapy for Outpatients With Schizophrenia	https://ClinicalTrials.gov/show/NCT03794076	Recruiting	University of Pittsburgh	2021-06-30
NCT03751488	A Study to Determine Pharmacokinetic Characteristics of LY03010 Versus INVEGA SUSTENNA® in Schizophrenia Patients	https://ClinicalTrials.gov/show/NCT03751488	Completed	Luye Pharma Group Ltd.	2019-07-24
NCT03739671	Vitamin D Supplementation and Effects on Mood in Emergency Medicine Residents	https://ClinicalTrials.gov/show/NCT03739671	Active, not recruiting	Spectrum Health - Lakeland	2019-03-31
NCT03736538	Nitrous Oxide- Suicidal Ideation	https://ClinicalTrials.gov/show/NCT03736538	Enrolling by invitation	Washington University School of Medicine	2021-10-31
NCT03715400	Mobile Virtual Positive Experiences for Anhedonia	https://ClinicalTrials.gov/show/NCT03715400	Recruiting	University of California, Los Angeles	2021-01-01
NCT03705143	Behavioral Activation for Heroin Use in China: A Randomized Controlled Trial	https://ClinicalTrials.gov/show/NCT03705143	Completed	University of North Carolina, Chapel Hill	2018-12-05
NCT03691792	Optimizing Long-Term Outcomes for Winter Depression With CBT-SAD and Light Therapy	https://ClinicalTrials.gov/show/NCT03691792	Recruiting	University of Vermont	2023-02-28
NCT03680664	Mindfulness-Based Stress Reduction (MBSR) and Transcranial Direct Current Stimulation (tDCS)	https://ClinicalTrials.gov/show/NCT03680664	Completed	Centre for Addiction and Mental Health	2019-07-04
NCT03671525	Cognitive Effects of Nimodipine in Patients With Schizophrenia	https://ClinicalTrials.gov/show/NCT03671525	Recruiting	Johns Hopkins University	2020-10-31
NCT03667729	The Effects of Progressive Muscle Relaxation Therapy in Patients With Schizophrenia	https://ClinicalTrials.gov/show/NCT03667729	Completed	Taipei Medical University	2015-06-29
NCT03639831	ACUTE AND CHRONIC EFFECTS OF A BOTANICAL EXTRACT ON ANXIETY, PERCEIVED STRESS, MOOD AND CORTISOL IN HEALTHY ADULTS	https://ClinicalTrials.gov/show/NCT03639831	Completed	Activ’inside	2018-11-15
NCT03622749	Pilot Study of Neuromodulation for Enhancement of Emotion Regulation in Bipolar Mood Disorders	https://ClinicalTrials.gov/show/NCT03622749	Recruiting	Massachusetts General Hospital	2020-04-01
NCT03609515	Patient-controlled Admissions in Inpatient Mental Health Services	https://ClinicalTrials.gov/show/NCT03609515	Completed	University Hospital, Akershus	2012-12-31
NCT03603561	Continuous Theta Burst Stimulation as an add-on Treatment for Bipolar Depression	https://ClinicalTrials.gov/show/NCT03603561	Recruiting	Universiteit Antwerpen	2020-07-31
NCT03575728	Telemetry-Triggered Educational Content Delivery Using MyChart in Mood Disorders	https://ClinicalTrials.gov/show/NCT03575728	Completed	Sunnybrook Health Sciences Centre	2019-12-15
NCT03575442	“Art Therapy” in Acute Psychiatry	https://ClinicalTrials.gov/show/NCT03575442	Active, not recruiting	Centro Hospitalar e Universitário de Coimbra, E.P.E.	2018-03-01
NCT03572790	Effects of Seven Day Prucalopride Administration in Healthy Volunteers	https://ClinicalTrials.gov/show/NCT03572790	Recruiting	University of Oxford	2020-03-31
NCT03538860	Validation of an Automated Online Language Interpreting Tool - Phase Two.	https://ClinicalTrials.gov/show/NCT03538860	Recruiting	University of California, Davis	2021-07-31
NCT03523767	Effect of Systemic Inflammation on Emotion and Cognition in Patients With Mood Disorder - A Vaccine Study	https://ClinicalTrials.gov/show/NCT03523767	Recruiting	The University of Texas Health Science Center, Houston	2020-02-29
NCT03515486	Cerebellar Stroke and Mood Disorders	https://ClinicalTrials.gov/show/NCT03515486	Active, not recruiting	University Hospital, Bordeaux	2020-12-16
NCT03460756	A Clinical Trial of Oral Ganaxolone in Women With Postpartum Depression	https://ClinicalTrials.gov/show/NCT03460756	Completed	Marinus Pharmaceuticals	2019-07-05
NCT03449771	PrEP and Consumptions	https://ClinicalTrials.gov/show/NCT03449771	Completed	University Hospital, Montpellier	2019-02-26
NCT01244854	Life Goals Behavioral Change to Improve Outcomes for Veterans With Serious Mental Illness	https://ClinicalTrials.gov/show/NCT01244854	Completed	VA Office of Research and Development	2012-08-13
NCT01243606	Efficacy Evaluation of a Unified Transdiagnostic Treatment for Anxiety Disorders	https://ClinicalTrials.gov/show/NCT01243606	Completed	Boston University Charles River Campus	2017-05-31
NCT01189812	Safety and Efficacy Study of Citalopram and Lithium for the Treatment of Depressive Mood Disorder Symptoms	https://ClinicalTrials.gov/show/NCT01189812	Completed	Columbia Northwest Pharmaceuticals	2011-01-31
NCT01149135	Low Intensity ‘Blue Light’ Treatment of Seasonal Affective Disorder	https://ClinicalTrials.gov/show/NCT01149135	Completed	University Medical Center Groningen	2009-03-31
NCT01136278	Pharmacological Interaction Between Clonidine and Methylenedioxymethamphetamine (MDMA)	https://ClinicalTrials.gov/show/NCT01136278	Completed	University Hospital, Basel, Switzerland	2010-12-31
NCT01048294	Blue Enriched Versus Standard Light Treatment for Seasonal Affective Disorder(SAD)	https://ClinicalTrials.gov/show/NCT01048294	Completed	University Medical Center Groningen	2006-03-31
NCT01003132	Assessing the Effectiveness of Acceptance and Commitment Therapy for Distress Following Psychosis	https://ClinicalTrials.gov/show/NCT01003132	Completed	University of Glasgow	2010-10-31
NCT00990067	Interaction Between Duloxetine and 3,4-Methylenedioxymethamphetamine (MDMA, Ecstasy)	https://ClinicalTrials.gov/show/NCT00990067	Completed	University Hospital, Basel, Switzerland	2010-05-31
NCT00988104	Preventing Long Term Psychiatric Disability Among Those With Major Burn Injuries	https://ClinicalTrials.gov/show/NCT00988104	Completed	Johns Hopkins University	2015-10-15
NCT00960375	Smoking Cessation for Veterans With Severe and Persistent Mental Illness	https://ClinicalTrials.gov/show/NCT00960375	Completed	VA Office of Research and Development	2014-03-31
NCT00916552	Effects of Erythropoietin on Depressive Symptoms and Neurocognitive Deficits in Depression and Bipolar Disorder	https://ClinicalTrials.gov/show/NCT00916552	Completed	Rigshospitalet, Denmark	2012-10-31
NCT00912535	Quetiapine Augmentation for Primary Anxiety Disorder or Mood Disorders With Co-morbid Anxiety Symptoms	https://ClinicalTrials.gov/show/NCT00912535	Completed	Chang Gung Memorial Hospital	2010-07-31
NCT00895804	Pharmacological Interaction Between Pindolol and MDMA (3,4-Methylenedioxymethamphetamine)	https://ClinicalTrials.gov/show/NCT00895804	Completed	University Hospital, Basel, Switzerland	2002-03-31
NCT00886886	Interaction Between Reboxetine and 3,4-Methylenedioxymethamphetamine: Pharmacodynamics (PD) and Pharmacokinetics (PK)	https://ClinicalTrials.gov/show/NCT00886886	Completed	University Hospital, Basel, Switzerland	2009-12-31
NCT02120937	Mindfulness in Mood Dysregulated Youth	https://ClinicalTrials.gov/show/NCT02120937	Completed	University of Cincinnati	2016-03-31
NCT03743844	Psychosocial Intervention for Women With Mood Disorders Seeking Treatment for Obesity	https://ClinicalTrials.gov/show/NCT03743844	Completed	Western University, Canada	2020-03-13
NCT00809523	A Trial of Negative Ion Generation Versus Light-Emitting Diode Phototherapy for Seasonal Affective Disorder (SAD)	https://ClinicalTrials.gov/show/NCT00809523	Completed	Yale University	2010-04-30
NCT01547026	Self-regulation Strategies to Improve Exercise Behavior Among Schizophrenic Patients	https://ClinicalTrials.gov/show/NCT01547026	Completed	University of Konstanz	2012-10-31
NCT03310593	Cannabidiol as an Adjunctive Treatment for Bipolar Depression	https://ClinicalTrials.gov/show/NCT03310593	Recruiting	Hospital de Clinicas de Porto Alegre	2022-02-28
NCT02578758	Efficacy of a Transdiagnostic Internet-based Protocol in Community Sample	https://ClinicalTrials.gov/show/NCT02578758	Active, not recruiting	Universitat Jaume I	2019-11-30
NCT02308462	Implementation and Evaluation of a Family-based Intervention Program for Children of Mentally Ill Parents	https://ClinicalTrials.gov/show/NCT02308462	Active, not recruiting	Universitätsklinikum Hamburg-Eppendorf	2019-06-30
NCT01818453	Can Genetics Predict Treatment Response to a Computerized Self-help Program for Depression?	https://ClinicalTrials.gov/show/NCT01818453	Completed	University of Texas at Austin	2015-11-30
NCT04354974	Evaluation of a Cognitive Remediation Program for Mood Disorders	https://ClinicalTrials.gov/show/NCT04354974	Recruiting	Centre hospitalier de Ville-Evrard, France	2022-02-18
NCT04268303	Dexmedetomidine in the Treatment of Agitation Associated With Schizophrenia	https://ClinicalTrials.gov/show/NCT04268303	Recruiting	BioXcel Therapeutics Inc	2020-05-01
NCT04099771	Ketamine for Mood Disorders With Suicidal Ideation	https://ClinicalTrials.gov/show/NCT04099771	Recruiting	The Miriam Hospital	2020-12-31
NCT03925038	Electronic Communication Augmented Mental Health Care	https://ClinicalTrials.gov/show/NCT03925038	Recruiting	Johns Hopkins University	2021-12-30
NCT00748956	Intranasal Administration of Neuropeptide Y in Healthy Male Volunteers	https://ClinicalTrials.gov/show/NCT00748956	Completed	Icahn School of Medicine at Mount Sinai	2010-12-31
NCT00704379	Treatment Strategy to Prevent Mood Disorders Following Traumatic Brain Injury	https://ClinicalTrials.gov/show/NCT00704379	Completed	Baylor College of Medicine	2014-04-30
NCT00699218	A Pilot Study on Repetitive Transcranial Magnetic Stimulation (rTMS) Treatment of Bipolar Depression	https://ClinicalTrials.gov/show/NCT00699218	Completed	University of California, Davis	2009-07-31
NCT00663871	Evaluating the Effects of Omega-3 Fatty Acids on Heart Disease and Behavior	https://ClinicalTrials.gov/show/NCT00663871	Completed	University of Pittsburgh	2012-04-30
NCT00616915	Does Sleep Quality Change After Switch From Wellbutrin SR to Wellbutrin XL in Patients With Major Depressive Disorder?	https://ClinicalTrials.gov/show/NCT00616915	Completed	Queen’s University	2009-01-31
NCT00593099	A Preliminary Study of Sustained-Release Bupropion for Smoking Cessation in Bipolar Affective Disorder	https://ClinicalTrials.gov/show/NCT00593099	Completed	National Institute on Drug Abuse (NIDA)	2006-06-30
NCT00579982	An Open-Label Trial Measuring Satisfaction And Convenience Of Two Formulations Of Lamotrigine In Subjects With A Mood Disorder	https://ClinicalTrials.gov/show/NCT00579982	Completed	GlaxoSmithKline	2008-02-29
NCT00578383	Low Field Magnetic Stimulation in Mood Disorders Using the LFMS Device	https://ClinicalTrials.gov/show/NCT00578383	Completed	Mclean Hospital	2011-03-31
NCT00521417	Short- and Long-term Group Psychotherapy	https://ClinicalTrials.gov/show/NCT00521417	Active, not recruiting	University of Oslo	2018-08-31
NCT00515671	Illness Management and Recovery for Veterans With Severe Mental Illness	https://ClinicalTrials.gov/show/NCT00515671	Completed	VA Office of Research and Development	2012-04-30
NCT00502320	Ramelteon in the Treatment of Sleep and Mood in Patients With Seasonal Affective Disorder	https://ClinicalTrials.gov/show/NCT00502320	Completed	Lehigh Valley Hospital	2008-04-30
NCT00488748	Magnetic Seizure Therapy (MST) for Severe Mood Disorder	https://ClinicalTrials.gov/show/NCT00488748	Completed	Duke University	2012-08-31
NCT00480571	Safety and Tolerability of BL-1020 in Hospitalized Subjects With Chronic Schizophrenia or Schizo-Affective Disorder	https://ClinicalTrials.gov/show/NCT00480571	Completed	BioLineRx, Ltd.	2007-12-31
NCT00463372	Study Investigating the Safety and Tolerability of Multiple Doses of PF-02545920 in Subjects With Schizophrenia	https://ClinicalTrials.gov/show/NCT00463372	Completed	Pfizer	NA
NCT00459264	Prevention of Mood Disorders by Folic Acid Supplementation	https://ClinicalTrials.gov/show/NCT00459264	Completed	University of Oxford	2011-06-30
NCT00447733	Integrated Treatment to Persons With Mental Disorders and Co-occurring Substance Use Disorders	https://ClinicalTrials.gov/show/NCT00447733	Completed	University of Oslo	2010-12-31
NCT00423462	First Experimental Study of Transference-Interpretations (FEST)	https://ClinicalTrials.gov/show/NCT00423462	Completed	University of Oslo	NA
NCT00421070	Effect of Massage Therapy on Aggression in a Psychiatric Inpatient Unit	https://ClinicalTrials.gov/show/NCT00421070	Completed	Melbourne Health	2006-09-30
NCT00393874	Efficacy of Sleep Interventions for Posttraumatic Stress Disorder (PTSD)	https://ClinicalTrials.gov/show/NCT00393874	Completed	University of Pittsburgh	2010-06-30
NCT00340379	Ziprasidone vs. Sertraline/Haloperidol in Psychotic Depression	https://ClinicalTrials.gov/show/NCT00340379	Completed	Duke University	2005-08-31
NCT00338806	Early Detection and Prevention of Mood Disorders in Children of Parents With Bipolar Disorder	https://ClinicalTrials.gov/show/NCT00338806	Completed	New York State Psychiatric Institute	2012-07-31
NCT00309699	A Study to Evaluate the Efficacy and Safety of Flexible Doses of Extended-release (ER) Paliperidone Compared With Flexible Doses of Quetiapine and Placebo in Patients With Bipolar I Disorder	https://ClinicalTrials.gov/show/NCT00309699	Completed	Johnson & Johnson Pharmaceutical Research & Development, L.L.C.	2007-09-30
NCT00299715	A Study to Evaluate the Efficacy and Safety of Three Fixed Doses of Extended-release Paliperidone in Subjects With Bipolar I Disorder	https://ClinicalTrials.gov/show/NCT00299715	Completed	Johnson & Johnson Pharmaceutical Research & Development, L.L.C.	2007-06-30
NCT00295139	Behavioral Treatment of Drug Abuse in Severe and Persistent Mental Illness (SPMI) Patients	https://ClinicalTrials.gov/show/NCT00295139	Completed	University of Maryland, Baltimore	2010-03-31
NCT00291031	Study of the Effect of Imagery Rehearsal Therapy (IRT) of Nightmares	https://ClinicalTrials.gov/show/NCT00291031	Completed	GGZ Centraal	2011-01-31
NCT00288782	PET Neuroimaging of [11C]Mirtazapine	https://ClinicalTrials.gov/show/NCT00288782	Completed	University of Aarhus	NA
NCT00287352	Study of Amantadine for Weight Stabilization During Olanzapine Treatment	https://ClinicalTrials.gov/show/NCT00287352	Completed	University of North Carolina, Chapel Hill	2009-09-30
NCT00280813	Alcohol Use Disorders in Schizophrenia	https://ClinicalTrials.gov/show/NCT00280813	Completed	University of Maryland, Baltimore	2007-05-31
NCT00269633	Research Study of Treatment for Winter Depression With Different Colors of Light	https://ClinicalTrials.gov/show/NCT00269633	Completed	Thomas Jefferson University	2008-05-31
NCT00253071	Early Integrated Intervention in Severe Affective Disorders	https://ClinicalTrials.gov/show/NCT00253071	Completed	Hovedstadens Sygehusfaelesskab	2012-03-31
NCT00240721	A Study of the Effectiveness and Safety of Topiramate in the Treatment of Patients With Bipolar Disorder	https://ClinicalTrials.gov/show/NCT00240721	Completed	Johnson & Johnson Pharmaceutical Research & Development, L.L.C.	NA
NCT00239122	Recovery Therapy Trial	https://ClinicalTrials.gov/show/NCT00239122	Completed	Melbourne Health	NA
NCT00227812	Integrated Treatment for Cocaine and Mood Disorders - 1	https://ClinicalTrials.gov/show/NCT00227812	Completed	National Institute on Drug Abuse (NIDA)	2005-12-31
NCT00221468	A Study of Quetiapine for the Treatment of Mood Disorders in Adolescents	https://ClinicalTrials.gov/show/NCT00221468	Completed	University of Cincinnati	2006-04-30
NCT00217932	Effectiveness of Divalproex Sodium (Depakote) in Treating Children With Temper Outbursts and Severe Mood Swings	https://ClinicalTrials.gov/show/NCT00217932	Completed	National Institute on Drug Abuse (NIDA)	NA
NCT00211250	Comparing Compliance, Tolerability, Efficacy and Adverse Events in Bipolar Tients From Valproic Acid to Depakote ER	https://ClinicalTrials.gov/show/NCT00211250	Completed	Joliet Center for Clinical Research	2006-07-31
NCT00206544	Anti-Estrogens - A Potential Treatment for Bipolar Affective Disorder in Women?	https://ClinicalTrials.gov/show/NCT00206544	Completed	The Alfred	2007-12-31
NCT00202514	Placebo Controlled Trial of Depakote ER in Alcohol Dependent Patients With Mood and/or Anxiety Symptoms	https://ClinicalTrials.gov/show/NCT00202514	Completed	Seattle Institute for Biomedical and Clinical Research	2006-07-31
NCT00199940	Safety And Efficacy Study Of Ziprasidone In Pediatric Psychotic Illness	https://ClinicalTrials.gov/show/NCT00199940	Completed	Medical College of Wisconsin	NA
NCT00186758	Transcranial Magnetic Stimulation in Bipolar Depression	https://ClinicalTrials.gov/show/NCT00186758	Completed	St. Joseph’s Healthcare Hamilton	2011-07-31
NCT00178828	Dynamic Measures of Neurochemistry in Mood Disorders	https://ClinicalTrials.gov/show/NCT00178828	Completed	Vanderbilt University Medical Center	2013-04-30
NCT00177567	Treatment of Geriatric Bipolar Mood Disorders: A Pilot Study	https://ClinicalTrials.gov/show/NCT00177567	Completed	University of Pittsburgh	NA
NCT00149617	Effectiveness of Buspirone and Motivational Enhancement Therapy for the Treatment of Marijuana Dependence - 1	https://ClinicalTrials.gov/show/NCT00149617	Completed	Medical University of South Carolina	NA
NCT00139997	Environmental Treatment for Seasonal Affective Disorder (SAD)	https://ClinicalTrials.gov/show/NCT00139997	Completed	Yale University	2005-08-31
NCT00137306	Facilitating the Adoption of Evidence-Based Depression Management in Substance Use Treatment Programs	https://ClinicalTrials.gov/show/NCT00137306	Completed	VA Office of Research and Development	2006-10-31
NCT00137189	Resource-oriented Music Therapy for Psychiatric Patients With Low Therapy Motivation	https://ClinicalTrials.gov/show/NCT00137189	Completed	NORCE Norwegian Research Centre AS	2010-10-31
NCT00105378	Dutch EASYcare Study	https://ClinicalTrials.gov/show/NCT00105378	Completed	Radboud University	NA
NCT00088699	Rapid Antidepressant Effects of Ketamine in Major Depression	https://ClinicalTrials.gov/show/NCT00088699	Completed	National Institutes of Health Clinical Center (CC)	2017-07-31
NCT00082043	Dutasteride to Treat Women With Menstrually Related Mood Disorders	https://ClinicalTrials.gov/show/NCT00082043	Completed	National Institutes of Health Clinical Center (CC)	2014-03-06
NCT00076245	Cognitive Behavioral Therapy for the Treatment of Seasonal Affective Disorder (SAD)	https://ClinicalTrials.gov/show/NCT00076245	Completed	Henry M. Jackson Foundation for the Advancement of Military Medicine	2004-02-29
NCT00050557	Family Psychoeducation for Children With Mood Disorders	https://ClinicalTrials.gov/show/NCT00050557	Completed	Ohio State University	2006-09-30
NCT00001482	New Drugs in the Treatment of Mood Disorders	https://ClinicalTrials.gov/show/NCT00001482	Completed	National Institutes of Health Clinical Center (CC)	NA
NCT00046449	Prevention of Seasonal Affective Disorder	https://ClinicalTrials.gov/show/NCT00046449	Completed	GlaxoSmithKline	2003-06-30
NCT00046241	Prevention of Seasonal Affective Disorder	https://ClinicalTrials.gov/show/NCT00046241	Completed	GlaxoSmithKline	2003-06-30
NCT00035802	A Study to Evaluate the Safety and Effectiveness of Topiramate Compared to Placebo in the Treatment of Patients With Bipolar I Disorder	https://ClinicalTrials.gov/show/NCT00035802	Completed	Johnson & Johnson Pharmaceutical Research & Development, L.L.C.	NA
NCT00794040	A Controlled Trial of Serotonin Reuptake Inhibitors Added to Stimulant Medication in Youth With Severe Mood Dysregulation	https://ClinicalTrials.gov/show/NCT00794040	Completed	National Institutes of Health Clinical Center (CC)	2018-02-01
NCT00006517	Clinical Trials of Three Non-Drug Treatments for Winter Depression (SAD)	https://ClinicalTrials.gov/show/NCT00006517	Completed	New York State Psychiatric Institute	2003-06-30
NCT00006172	Clinical Trials of Two Non-drug Treatments for Chronic Depression	https://ClinicalTrials.gov/show/NCT00006172	Completed	New York State Psychiatric Institute	2003-07-31
NCT00001545	Evaluation of Repetitive Transcranial Magnetic Stimulation (rTMS) in the Treatment of Mood Disorders	https://ClinicalTrials.gov/show/NCT00001545	Completed	National Institutes of Health Clinical Center (CC)	NA
NCT00001487	Treatment of Mid-Life-Related Mood Disorders	https://ClinicalTrials.gov/show/NCT00001487	Completed	National Institutes of Health Clinical Center (CC)	NA
NCT00001146	Omega-3 Fatty Acids in the Treatment of Bipolar Disorder: A Double-Blind, Placebo-Controlled Trial	https://ClinicalTrials.gov/show/NCT00001146	Completed	National Institutes of Health Clinical Center (CC)	NA
NCT00016666	Clinical Trial of Propranolol for Seasonal Affective Disorder	https://ClinicalTrials.gov/show/NCT00016666	Completed	National Institutes of Health Clinical Center (CC)	NA

Observational Studiess

#If less then 500 studies

nct_id	brief_title	link	overall_status	source	primary_completion_date
NCT00071786	Family Study of Affective and Anxiety Spectrum Disorders	https://ClinicalTrials.gov/show/NCT00071786	Recruiting	National Institutes of Health Clinical Center (CC)	NA
NCT04339790	Mental Health Impact of COVID-19 Pandemic on NIMH Research Participants and Volunteers	https://ClinicalTrials.gov/show/NCT04339790	Recruiting	National Institutes of Health Clinical Center (CC)	2022-03-01
NCT03335696	Predicting MRI Abnormalities With Longitudinal Data of the Whitehall II Substudy	https://ClinicalTrials.gov/show/NCT03335696	Completed	University of Oxford	2017-06-30
NCT03294525	Towards Neurobiology-based Diagnosis and Treatment of Affective Disorders	https://ClinicalTrials.gov/show/NCT03294525	Recruiting	Peking University	2020-12-31
NCT03235908	Copeptin in Outcome Prediction of an Acute Psychotic Episode	https://ClinicalTrials.gov/show/NCT03235908	Active, not recruiting	University Hospital, Basel, Switzerland	2020-07-31
NCT02799524	Comparison of Mood Disorders Screening Scales in Geriatric Oncology	https://ClinicalTrials.gov/show/NCT02799524	Completed	University Hospital, Caen	2016-12-31
NCT02773108	Somatic Comorbidities in Psychiatric Patients	https://ClinicalTrials.gov/show/NCT02773108	Completed	Sveti Ivan Psychiatric Hospital	2016-06-30
NCT02761720	Mobile App for Mood in Pregnancy (Ginger iO)	https://ClinicalTrials.gov/show/NCT02761720	Completed	University of Pennsylvania	2015-11-30
NCT02596698	Mitochondrial Dysfunction, Inflammation, and White Matter Integrity in Youth With Mood Disorders	https://ClinicalTrials.gov/show/NCT02596698	Completed	University of Minnesota	2018-03-31
NCT00001177	Study of Premenstrual Syndrome and Premenstrual Dysphoria	https://ClinicalTrials.gov/show/NCT00001177	Recruiting	National Institutes of Health Clinical Center (CC)	NA
NCT02566980	Biological Triggers of Depression in Pregnancy	https://ClinicalTrials.gov/show/NCT02566980	Completed	Michigan State University	2017-02-28
NCT00397111	Development of Magnetic Resonance Imaging Techniques for Studying Mood and Anxiety Disorders	https://ClinicalTrials.gov/show/NCT00397111	Recruiting	National Institutes of Health Clinical Center (CC)	NA
NCT00006177	Child & Adolescent Bipolar Disorder Brain Imaging and Treatment Study	https://ClinicalTrials.gov/show/NCT00006177	Completed	National Institutes of Health Clinical Center (CC)	NA
NCT02321943	Anomalous Self-Experience in First Episode Psychosis - A Six-Year Follow-Up Study	https://ClinicalTrials.gov/show/NCT02321943	Completed	Sykehuset Innlandet HF	2016-12-31
NCT02242669	Enhancing Outcomes, Reducing Costs: Evaluating Peer Support for Mood Disorders	https://ClinicalTrials.gov/show/NCT02242669	Completed	Massachusetts General Hospital	2017-04-30
NCT02083978	Bipolar Research Study Using MR Imaging	https://ClinicalTrials.gov/show/NCT02083978	Completed	Washington University Early Recognition Center	2014-12-31
NCT01292889	Study of Genes in Relation to Seasonal Affective Disorder and Major Depressive Disorder	https://ClinicalTrials.gov/show/NCT01292889	Completed	University of Pittsburgh	2011-12-31
NCT01272531	Pharmacogenomics of Mood Stabilizer Response in Bipolar Disorder (PGBD)	https://ClinicalTrials.gov/show/NCT01272531	Completed	University of California, San Diego	2016-04-30
NCT01272518	Assessment of Cardiac Autonomic Behavior in Patients With Mood Disorders	https://ClinicalTrials.gov/show/NCT01272518	Recruiting	Sao Jose do Rio Preto Medical School	2019-09-30
NCT01269710	Second-Generation Antipsychotic Treatment Indication Effectiveness And Tolerability In Youth (Satiety) Study	https://ClinicalTrials.gov/show/NCT01269710	Completed	University of North Carolina, Chapel Hill	2011-03-31
NCT02036606	Racing and Crowded Thoughts in Mood Disorders	https://ClinicalTrials.gov/show/NCT02036606	Recruiting	University Hospital, Strasbourg, France	2019-04-30
NCT01754532	Correlation Between Clinical Deterioration in Schizophrenic Patients and Hair Cortisol Levels	https://ClinicalTrials.gov/show/NCT01754532	Completed	Shalvata Mental Health Center	2015-06-30
NCT01583569	Complex Dynamic Systems in Mood Disorders	https://ClinicalTrials.gov/show/NCT01583569	Completed	Massachusetts General Hospital	2014-06-30
NCT01533064	Response of Psychiatric Outpatients to the Great East Japan Earthquake	https://ClinicalTrials.gov/show/NCT01533064	Completed	Ashikaga Red Cross Hospital	NA
NCT01518049	Clinical Validation of the Rating Scale for Psychotic Depression (RAS-PD)	https://ClinicalTrials.gov/show/NCT01518049	Completed	Aarhus University Hospital	2013-09-30
NCT01385709	The Influence of the Menstrual Cycle on Lithium and Sertraline Blood Levels	https://ClinicalTrials.gov/show/NCT01385709	Completed	Weill Medical College of Cornell University	2012-08-31
NCT04232267	Analysis of Sleep Study Data to Assess Depressive Burden	https://ClinicalTrials.gov/show/NCT04232267	Recruiting	Medibio Limited	2021-01-31
NCT04137471	Validation of the Ontological Addiction Scale	https://ClinicalTrials.gov/show/NCT04137471	Recruiting	University Hospital, Montpellier	2021-03-01
NCT04114565	Prevalence of Mood Disorders and Mental Health Service Use Among Immigrants in Santiago, Chile	https://ClinicalTrials.gov/show/NCT04114565	Recruiting	Pontificia Universidad Catolica de Chile	2019-11-30
NCT03919760	Early Psychosis Intervention - Spreading Evidence-based Treatment	https://ClinicalTrials.gov/show/NCT03919760	Recruiting	Centre for Addiction and Mental Health	2023-05-31
NCT03774641	A Pilot Study of Prophylactic Management of Lamotrigine in Pregnant Women	https://ClinicalTrials.gov/show/NCT03774641	Recruiting	Johns Hopkins University	2020-12-31
NCT03736057	Genetic Evaluation for Medication Selection (GEMS) Study	https://ClinicalTrials.gov/show/NCT03736057	Completed	University of Alabama at Birmingham	2018-08-14
NCT03711045	An Eye Tracking Study of Affective Disorder Patients With Suicide Risk	https://ClinicalTrials.gov/show/NCT03711045	Recruiting	Central South University	2019-12-31
NCT03615794	A Study of Pregnant and Postpartum Women With and Without Mood Disorders	https://ClinicalTrials.gov/show/NCT03615794	Recruiting	Johns Hopkins University	2021-10-31
NCT03558529	Feasibility and Acceptability of a Smartphone App to Assess Early Warning Signs of Psychosis Relapse	https://ClinicalTrials.gov/show/NCT03558529	Completed	Manchester Academic Health Science Centre	2018-04-01
NCT03429361	Testing the Value of Smartphone Assessments of People With Mood Disorders	https://ClinicalTrials.gov/show/NCT03429361	Completed	Mindstrong	2019-05-30
NCT01184235	Multidimensional Measurement of Psychopharmacological Treatment Response	https://ClinicalTrials.gov/show/NCT01184235	Completed	Child Psychopharmacology Institute	2011-08-31
NCT01125579	Effectiveness of NEURAPAS Balance in Children With Nervous Restlessness	https://ClinicalTrials.gov/show/NCT01125579	Completed	Pascoe Pharmazeutische Praeparate GmbH	2008-11-30
NCT01106313	Insulin Resistance in Patients With Major Depression	https://ClinicalTrials.gov/show/NCT01106313	Completed	Stanford University	2016-01-31
NCT01032421	Gonadal Steroid Manipulation and Personality Characteristics: Association With Mood Fluctuations and in Vitro Fertilization (IVF) Outcomes	https://ClinicalTrials.gov/show/NCT01032421	Completed	Tel-Aviv Sourasky Medical Center	2007-12-31
NCT03004872	Relationship Between Postpartum Mood Disorders and Delivery Experience	https://ClinicalTrials.gov/show/NCT03004872	Completed	University of Michigan	2018-12-17
NCT02675712	Effect of African Drumming in Mood Disorders	https://ClinicalTrials.gov/show/NCT02675712	Completed	University of Stellenbosch	2015-06-30
NCT00001231	Perimenopause-Related Mood and Behavioral Disorders	https://ClinicalTrials.gov/show/NCT00001231	Recruiting	National Institutes of Health Clinical Center (CC)	NA
NCT04036877	Mood Disorders Bladder Cancer	https://ClinicalTrials.gov/show/NCT04036877	Recruiting	University of Kansas Medical Center	2021-07-31
NCT00742365	Predicting Effectiveness of Light Treatment for Winter Seasonal Affective Disorder	https://ClinicalTrials.gov/show/NCT00742365	Completed	University of Maryland, Baltimore	2010-04-30
NCT00741299	A Study of the Association Between Tobacco Smoking and Bipolar Affective Disorder	https://ClinicalTrials.gov/show/NCT00741299	Completed	Tirat Carmel Mental Health Center	2009-07-31
NCT00683709	Specialized Clozapine Clinic for Bipolar and Schizoaffective Disorder	https://ClinicalTrials.gov/show/NCT00683709	Completed	St. Joseph’s Healthcare Hamilton	2011-07-31
NCT00627510	Routine Plasma Level Determination to Compare Actual vs Expected Plasma Levels at Psychiatric Inpatient Admission	https://ClinicalTrials.gov/show/NCT00627510	Completed	Medical University Innsbruck	2005-07-31
NCT00325065	Identifying the Role of Oxytocin and Vasopressin in the Functioning of Neurocognitive Systems Involved in Mood Disorders	https://ClinicalTrials.gov/show/NCT00325065	Completed	National Institutes of Health Clinical Center (CC)	NA
NCT00312598	Body Mass Index (BMI) and Metabolic Changes Following Switch to Aripiprazole From Olanzapine, Risperidone and Quetiapine	https://ClinicalTrials.gov/show/NCT00312598	Completed	University of North Carolina, Chapel Hill	2010-04-30
NCT00230425	The Measurement of Mood Variability and Sustained Attention in Women With Alcohol Dependence.	https://ClinicalTrials.gov/show/NCT00230425	Completed	University of Saskatchewan	NA
NCT00225459	Does Spiritual/Religious Commitment Mediate the Relationship Between Mood Variability and Suicidal Ideation.	https://ClinicalTrials.gov/show/NCT00225459	Completed	University of Saskatchewan	NA
NCT00163865	A Pilot Study of Boredom in a Community Sample of Adolescents and a Clinical Sample of Adolescents	https://ClinicalTrials.gov/show/NCT00163865	Completed	Bayside Health	2008-06-30
NCT00116077	Dopamine Receptor Imaging in Mood Disorders	https://ClinicalTrials.gov/show/NCT00116077	Completed	National Institutes of Health Clinical Center (CC)	NA
NCT00024635	Evaluation of Patients With Mood and Anxiety Disorders and Healthy Volunteers	https://ClinicalTrials.gov/show/NCT00024635	Recruiting	National Institutes of Health Clinical Center (CC)	NA
NCT00100360	Hormonal Causes of Menstrual-Related Mood Disorders	https://ClinicalTrials.gov/show/NCT00100360	Completed	National Institutes of Health Clinical Center (CC)	NA
NCT00097175	Effects of Tryptophan Depletion on Brain Processing of Emotions in Patients With Mood Disorders	https://ClinicalTrials.gov/show/NCT00097175	Completed	National Institutes of Health Clinical Center (CC)	NA
NCT00001485	Effects of Season on Melatonin Secretion in Healthy Men and Women and Patients With Seasonal Affective Disorder	https://ClinicalTrials.gov/show/NCT00001485	Completed	National Institutes of Health Clinical Center (CC)	NA
NCT00001479	Study of the Hypothalmic-Pituitary-Adrenal (HPA) Axis and Its Role in Major Depression	https://ClinicalTrials.gov/show/NCT00001479	Completed	National Institutes of Health Clinical Center (CC)	NA
NCT00001478	Effects of Drugs on Cerebral Blood Flow in Patients With Mood Disorders	https://ClinicalTrials.gov/show/NCT00001478	Completed	National Institutes of Health Clinical Center (CC)	NA
NCT00001232	The Effect of GnRH on Pitutitary Hormones in Menstrual-Cycle Mood Related Disorders	https://ClinicalTrials.gov/show/NCT00001232	Completed	National Institutes of Health Clinical Center (CC)	NA
NCT00026832	Examination of Brain Serotonin Receptors in Patients With Mood Disorders	https://ClinicalTrials.gov/show/NCT00026832	Completed	National Institutes of Health Clinical Center (CC)	NA
NCT00025935	Studies of Brain Function and Course of Illness in Pediatric Bipolar Disorder	https://ClinicalTrials.gov/show/NCT00025935	Recruiting	National Institutes of Health Clinical Center (CC)	NA
NCT00005557	Epidemiology of Sleep-Disordered Breathing in Adults	https://ClinicalTrials.gov/show/NCT00005557	Active, not recruiting	University of Wisconsin, Madison	2023-04-30
NCT00005011	Combined Hormone Replacement in Menstrually-Related Mood Disorders	https://ClinicalTrials.gov/show/NCT00005011	Completed	National Institutes of Health Clinical Center (CC)	NA
NCT00001770	Progestin (Progesterone-Like Hormones) Induced Dysphoria (Depressed Mood, Irritability, Anxiety)	https://ClinicalTrials.gov/show/NCT00001770	Completed	National Institutes of Health Clinical Center (CC)	NA
NCT00001654	The Role of Emotion in the Development of Psychopathology	https://ClinicalTrials.gov/show/NCT00001654	Completed	National Institutes of Health Clinical Center (CC)	NA
NCT00001192	Neuropsychological Evaluation of Psychiatric and Neurological Patients	https://ClinicalTrials.gov/show/NCT00001192	Completed	National Institutes of Health Clinical Center (CC)	NA
NCT00001170	Study of the Psychological Development of Children of Parents With and Without Affective Disorders	https://ClinicalTrials.gov/show/NCT00001170	Completed	National Institutes of Health Clinical Center (CC)	NA
NCT00016731	Adolescence, Puberty, and Emotion Regulation	https://ClinicalTrials.gov/show/NCT00016731	Completed	National Institutes of Health Clinical Center (CC)	NA
NCT00001919	Neuroimaging of St. John’s Wort-Induced Changes of Serotonin Metabolism in Normal Subjects	https://ClinicalTrials.gov/show/NCT00001919	Completed	National Institutes of Health Clinical Center (CC)	NA

Registries

#If less then 500 registries

nct_id	brief_title	link	overall_status	source	primary_completion_date
NCT03088657	Design and Methods of the Mood Disorder Cohort Research Consortium (MDCRC) Study	https://ClinicalTrials.gov/show/NCT03088657	Recruiting	Korea University Anam Hospital	2022-07-31
NCT02453438	Mood Patient Powered Research Network (MoodNetwork)	https://ClinicalTrials.gov/show/NCT02453438	Completed	Massachusetts General Hospital	2019-03-31
NCT02443636	The Canadian Depression Research and Intervention Network (CDRIN) Maritimes Registry	https://ClinicalTrials.gov/show/NCT02443636	Recruiting	Nova Scotia Health Authority	2025-01-31
NCT04298944	Association of Mood With Risk for Atherosclerosis	https://ClinicalTrials.gov/show/NCT04298944	Recruiting	Johns Hopkins University	2020-08-01
NCT04226963	A Naturalistic Study of Ketamine for Treatment Resistant Mood Disorders	https://ClinicalTrials.gov/show/NCT04226963	Recruiting	Medical University of Gdansk	2022-12-31
NCT03847753	Exploring the Comorbidity Between Mental Disorders and General Medical Conditions	https://ClinicalTrials.gov/show/NCT03847753	Completed	University of Aarhus	2016-12-31
NCT03724344	Correlation Study Between Mental Behavioral Symptoms in Dementia Patients and Mood Disorders of Caregivers	https://ClinicalTrials.gov/show/NCT03724344	Recruiting	Shanghai Mental Health Center	2019-08-31
NCT03458936	Resilience in Adolescent Development	https://ClinicalTrials.gov/show/NCT03458936	Recruiting	University of Texas Southwestern Medical Center	2031-12-31